Intralesional injections involve the introduction of medications or substances directly into a lesion, such as a tumor or inflammation, with the aim of reducing its size or alleviating associated symptoms. This procedure is performed using a fine needle and guided by ultrasound or other imaging techniques to ensure optimal precision and minimize the risk of complications.

In what ophthalmological conditions are these injections used?

These injections are an effective treatment option for a wide range of ophthalmological conditions, including:

  • Chalazion: This is an inflammation of the Meibomian glands located in the eyelids. Chalazia can be painful and affect vision. Intralesional corticosteroid injections can help reduce inflammation and alleviate symptoms.

  • Blepharitis: This is an inflammation of the eyelids that can cause itching, redness, crusting, and burning. Intralesional corticosteroid or antibiotic injections can be useful in controlling inflammation and infection.

  • Age-Related Macular Degeneration (AMD): In some cases, intralesional injections of anti-angiogenics may help slow the progression of AMD and preserve vision.

  • Diabetic Retinopathy: Intralesional injections of anti-angiogenics or corticosteroids can help control the growth of abnormal blood vessels in the retina, which can damage vision.

Advantages of Intralesional Injections

Finally, these injections offer several advantages compared to other treatments, such as:

  • Precision: The medication is administered directly to the affected area, minimizing exposure to the rest of the body.

  • Efficacy: They can be more effective than topical or oral treatments for certain conditions.

  • Minimization of Side Effects: Generally, they have fewer side effects than surgery.

  • Low Discomfort Procedure: The injection itself is quick and painless.